納菲制藥
Nasal-Phyto
Self-carrying carrier-free nasal cavity nano preparation brain-targeted delivery system and preparation method thereof
Transfer of application right of Xiamen University in November 2019;
Entered the actual review in May 2019;
The invention discloses a chiral oligosaccharide modified self-carrying carrier-free nasal cavity nano preparation brain-targeted delivery system. A method for preparing the above-mentioned nasal cavity nano preparation brain-targeted delivery system is also provided.
The preparation method of the system is simple, which can improve the hydrophobicity of small-molecule drugs, reduce toxicity, and enhance neuroprotective effects; no carrier, no biodegradation problems, and accumulated toxicity; good absorption through the membrane after modified by chitooligosaccharide, and high drug targeting Delivery into the brain.
The administration method of the dosage form is nasal drops, sprays, etc., and the operation is simple, which is convenient for patients taking long-term medication, and has good application prospects for the treatment of neurological diseases.
Ongoing: PCT patent, FDA drug delivery system application
The invention discloses a chiral oligosaccharide modified self-carrying carrier-free nasal cavity nano preparation brain-targeted delivery system. A method for preparing the above-mentioned nasal cavity nano preparation brain-targeted delivery system is also provided.
The preparation method of the system is simple, which can improve the hydrophobicity of small-molecule drugs, reduce toxicity, and enhance neuroprotective effects; no carrier, no biodegradation problems, and accumulated toxicity; good absorption through the membrane after modified by chitooligosaccharide, and high drug targeting Delivery into the brain.
The administration method of the dosage form is nasal drops, sprays, etc., and the operation is simple, which is convenient for patients taking long-term medication, and has good application prospects for the treatment of neurological diseases.
Ongoing: PCT patent, FDA drug delivery system application
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